cisnet.cancer.govCancer Intervention and Surveillance Modeling Network (CISNET) | SRP/DCCPS/NCI/NIH

An official website of the United States government Search Site Menu Search Home About About Funding History and Goals Organizational Structure Contact Us Awarded Grants CISNET V CISNET Incubator CISNET IV CISNET III CISNET I and II Modeling Approach Modeling Approach Comparative Modeling Multi-cohort Simulation Common Input Generators Model Documentation Cancer Sites Cancer Sites Bladder Breast Cervical Colorectal Gastric Lung Multiple Myeloma Prostate Uterine Esophageal (Historical) Impact Impact Highlights USPSTF / Other Collaborations NCI Bulletin Articles Resources Resources Policy and Individual Decision Tools Modeling Bridging Biological Mechanisms to Population Level Scales Publication Support and Modeling Resources Model Documentation Publications Publications By Cancer Site By Research Area Modeling to guide public health research and priorities CISNET is a consortium of NCI-sponsored investigators who use simulation modeling to improve our understanding of cancer control interventions in prevention, screening, and treatment and their effects on population trends in incidence and mortality. element, just before the first of the page. Use an empty to account for some browsers not moving keyboard focus after jump. * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * CISNET – Cancer Intervention and Surveillance Monitoring Network Highlights CISNET modeling quantifies the contributions of cancer risk, screening, tumor features, and treatment to racial disparities in mortality for 5 cancers Analyses by CISNET researchers quantified the contributions of different points along the cancer control continuum on disparities in cancer mortality rates for female breast, cervical, lung, prostate, and colorectal cancers between the overall U.S. and Black populations. read more CISNET multi-cancer site analysis highlighted the potential role of increased screening uptake in reducing cancer deaths and reaching the Cancer Moonshot goal A recent CISNET analysis estimated the contribution that increased uptake of screening tests could make toward the Biden Administration’s reignited Cancer Moonshot goal. read more CISNET models help explain why breast cancer mortality has declined since 1975 In this recent analysis published in JAMA, four CISNET models were used to estimate the contribution to the reduction in breast cancer mortality of changes in breast cancer screening and treatment since 1975. read more Cancer Sites Bladder Cancer Models focus on the natural course of the disease and will address questions on its prevention, diagnosis, treatment, and surveillance. Breast Cancer Models focus on critical early detection and clinical management issues, and are being used to evaluate mortality outcomes, harms and costs of rapidly evolving cancer control paradigms. Cervical Cancer Models focus on the natural history of human papillomavirus (HPV) and cervical carcinogenesis, the impact of HPV vaccination and screening, the comparative effectiveness of HPV vaccination and screening strategies, and approaches to reduce cervical cancer disparities. Colorectal Cancer Models focus on the natural history of the disease and the impact of interventions, including targeted screening, on mortality. Gastric Cancer Models are being used to produce innovative changes to gastric cancer care through a disparities oriented modeling approach focused on the most vulnerable, high-risk populations that bear the greatest gastric cancer burden. Lung Cancer Models focus on tobacco control policies and interventions in the US and other countries, lung cancer screening and early detection, targeted therapies and immunotherapies, and investigation of the synergistic impacts of those strategies. Multiple Myeloma Models focus on the natural history of the disease and the impact of novel strategies in preventing and treating multiple myeloma, with the goals of reducing its burden and mitigating disparities. Prostate Cancer Models focus on investigating risk-based screening and treatment strategies and approaches for reducing racial disparities. Uterine Cancer Models are being used to inform strategies for reducing uterine cancer incidence and mortality by improving prevention, screening, and treatment. Last Updated: 15 Apr, 2024The CISNET Website is a service of the Surveillance Research Program , in NCI’s Division of Cancer Control and Population SciencesAbout About About This Site Contact Us Resources Resources Cancer Sites Research Resources Policies Policies Accessibility FOIA Privacy & Security Disclaimers Vulnerability Disclosure Sign up for email updates Stay updated with the latest information on the SITE/ORG/INST by signing up for our email updates. Sign upCancer Intervention and Surveillance Modeling Network at the National Cancer Institute Contact Us Live Chat 1-800-4-CANCER NCIinfo@nih.govSite Feedback Follow us NCI Facebook NCI X NCI Instagram NCI YouTube NCI LinkedIn U.S. Department of Health and Human Services National Institutes of Health National Cancer Institute...